Product Details

SR-9011 is a synthetic compound classified as a Rev-ErbA agonist. It is currently studied in controlled research environments for its interaction with nuclear receptors involved in transcriptional regulation.

Within laboratory settings, SR-9011 is utilized to investigate receptor-ligand binding behavior and its influence on gene expression pathways. Its chemical structure supports consistent evaluation of nuclear receptor modulation and intracellular signaling dynamics.

This compound is supplied strictly for laboratory research purposes and is not intended for consumption, medical, or diagnostic use.

Mechanism of Action

At the molecular level, SR-9011 interacts with Rev-ErbA nuclear receptors, which function as transcriptional repressors within cellular systems. Upon binding, the compound-receptor complex influences the recruitment of corepressor proteins, leading to modulation of gene transcription.

This interaction is studied in vitro to examine how ligand binding affects transcriptional repression and regulatory signaling pathways. Researchers analyze changes in gene expression patterns associated with Rev-ErbA activation under controlled experimental conditions.

Additionally, SR-9011 is utilized to explore structure-dependent receptor selectivity and binding dynamics, contributing to a broader understanding of nuclear receptor-mediated transcriptional control.

Chemical Properties of SR-9011

Research Applications

Nuclear Receptor Binding Studies

SR-9011 is utilized in experimental systems to analyze ligand interaction with Rev-ErbA receptors. Researchers evaluate binding affinity and receptor engagement at the molecular level.

Transcriptional Regulation Analysis

This compound is applied in studies examining gene expression pathways influenced by nuclear receptor activity. These investigations focus on transcriptional repression mechanisms and cofactor recruitment.

Structure-Activity Relationship Research

SR-9011 supports investigations into how molecular structure influences receptor selectivity and signaling behavior. These studies contribute to a deeper understanding of ligand-receptor interactions.

Why Choose BehemothLabz to Buy SR-9011 for Research

BehemothLabz provides research-grade SR-9011 manufactured under controlled laboratory conditions with strict quality assurance protocols. Each batch undergoes analytical verification to ensure consistency in molecular composition and purity.

Comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility in experimental settings. BehemothLabz maintains a compliance-focused approach, supplying compounds intended strictly for laboratory-based investigation and analytical research

Disclaimer

SR-9011 is intended strictly for laboratory research and analytical purposes only. It is not intended for use in diagnostic procedures, therapeutic applications, or in vivo studies of any kind.

Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes. This compound must be handled exclusively by qualified professionals in controlled laboratory environments in accordance with applicable regulations and safety guidelines.

Improper handling or use outside of controlled research settings is strictly prohibited.

References

• Wolff, S. E. C., Wang, X. L., Jiao, H., Sun, J., Kalsbeek, A., Yi, C. X., & Gao, Y. (2020). The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia. Frontiers in immunology, 11, 550145. https://doi.org/10.3389/fimmu.2020.550145
• Solt, L. A., Wang, Y., Banerjee, S., Hughes, T., Kojetin, D. J., Lundasen, T., Shin, Y., Liu, J., Cameron, M. D., Noel, R., Yoo, S. H., Takahashi, J. S., Butler, A. A., Kamenecka, T. M., & Burris, T. P. (2012). Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature, 485(7396), 62–68. https://doi.org/10.1038/nature11030