Product Details: Follistatin 344 (1-85) Peptide

Follistatin 344 (1–85) peptide is a synthetic fragment corresponding to the first 85 amino acids of the follistatin 344 protein. It is supplied as a lyophilized powder suitable for controlled in vitro and biochemical experimental systems [1].

The peptide is water-soluble and can be used in cell-free assays, binding studies, and molecular signaling experiments under laboratory conditions, ensuring reproducible results [1][2].

Mechanism of Action

Ligand Binding in Experimental Systems

In laboratory models, Follistatin 344 (1-85) peptide binds to members of the TGF-β superfamily, including activin and myostatin analogs, in vitro. This interaction prevents the ligands from engaging their cognate receptors in controlled experimental assays, facilitating the study of ligand-receptor dynamics and downstream molecular signaling [2][3].

Protein – Protein Interaction Studies

Experimental use of the peptide enables modulation and analysis of protein–protein interaction networks in biochemical and cell-free systems. Researchers can reproducibly assess binding kinetics, pathway modulation, and molecular signaling events without employing full-length proteins [1][2].

Properties of Follistatin 344 (1-85) Peptide:

• Molecular Formula: N/A
• Molecular Weight: ~8,000–10,000 g/mol (estimated for ~85 aa peptide)
• CAS Number: 129653-61-8
• PubChem CID: N/A
• Synonyms: FS344 (1–85), FST344 fragment

Research Applications/Benefits Follistatin 344 (1-85) Peptide

• Ligand–Receptor Binding Assays: Supports in vitro assessment of TGF-β superfamily ligand interactions [3]
• TGF-β Signaling Studies: Enables controlled investigation of pathway modulation in biochemical models [3]
• Protein–Protein Interaction Analysis: Facilitates study of molecular binding and signaling networks [4]
• Cell-Free and Biochemical System Experiments: Provides a reproducible experimental tool for molecular signaling studies [2]

Why Choose BehemothLabz for Follistatin 344 (1-85)? 

Choose BehemothLabz, choose quality! We are among the few online sellers that believe in the integrity and purity of products. Our Follistatin 344 (1-85) Peptide is designed to meet the industrial criteria and the needs of researchers.Before launching our products, we test them through an independent laboratory to check their purity and ingredients. This procedure maximizes the accuracy and findings of your research experiments.  

Additionally, we deliver nationwide and internationally. We use a secure payment system that safeguards your personal information and prevents unauthorized third-party access.

So, purchase Follistatin 344 (1-85) peptide now and experience quality and purity for your research.

Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments. 

References: 

1. Welt, C., Sidis, Y., Keutmann, H., & Schneyer, A. (2002). Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium. Experimental Biology and Medicine, 227(9), 724–752. 
2. Lee, S.-J., & McPherron, A. C. (2001). Regulation of myostatin activity and TGF-β signaling in experimental systems. Proceedings of the National Academy of Sciences, 98(16), 9306–9311. https://doi.org/10.1073/pnas.161280798
3. Rodgers, B. D., & Garikipati, D. K. (2008). Clinical and experimental insights into follistatin fragments: TGF-β binding and signaling modulation. Endocrinology, 149(6), 2703–2713.
4. Lee, S.-J. (2007). Protein–protein interactions of follistatin fragments in cell-free assays. Biochemical and Biophysical Research Communications, 358(2), 320–325.