YK-11 (Myostine) is an investigational synthetic steroidal compound classified within the selective androgen receptor modulator (SARM) research category. It is supplied for laboratory-based research and intended for use in controlled experimental environments.

In preclinical and in vitro models, YK11 capsules are examined for their interaction with androgen receptor (AR) signaling pathways. Structurally derived from dihydrotestosterone (DHT), it exhibits partial agonistic activity at the androgen receptor in experimental systems. This distinguishes it from classical full agonists.

Mechanism of Action

In vitro studies indicate that YK-11 binds to the androgen receptor and functions as a partial agonist, leading to selective modulation of downstream transcriptional activity.

Experimental findings suggest that YK-11 influences the expression of follistatin, a regulatory protein associated with the transforming growth factor-beta (TGF-β) signaling network. This includes pathways related to myostatin. [1]

At the cellular level, YK-11 has been observed to:

• Modulate androgen receptor-mediated gene transcription. [3]
• Influence follistatin expression in myoblast-derived cell lines. [1]
• Affect signaling pathways involved in cellular differentiation and protein regulation. [1][2]

These observations are derived from controlled in vitro systems and remain under investigation in broader experimental models.

Properties YK-11 (Myostine) Capsules: 

• Molecular Formula: C₂₅H₃₄O₆
• Molecular Weight: 430.5 g/mol
• CAS Number: 1370003‑76‑1
• PubChem CID: 119058028
• Synonyms: YK-11 / Myostine 

Research Applications/Benefits of YK-11 (Myostine) Capsules 

YK-11 is utilized in research settings to investigate:

• Selective modulation of androgen receptor activity in in vitro systems. [1]
• Structure–activity relationships (SAR) of steroidal SARM analogs. [2]
• Regulation of follistatin expression in cellular research models. [1]
• Interactions between androgen signaling and TGF-β-associated pathways. [1]
• Mechanisms of receptor-selective transcriptional regulation. [3]

These applications are limited to laboratory and preclinical research and do not indicate clinical or therapeutic use.

Why choose BehemothLabz to buy YK11? 

Choose Behemoth Labz, choose quality! We are among the few online sellers that believe in the integrity and purity of products. We offer YK-11 for sale, which is designed to meet the industrial criteria and the needs of researchers. 

Before launching our products, we test them through an independent laboratory to check their purity and ingredients. This procedure maximizes the accuracy and findings of your research experiments.  

Additionally, we deliver nationwide and internationally. We use a secure payment system that safeguards your personal information and prevents unauthorized third-party access.

So, purchase YK-11 (Myostine)  now and experience quality and purity for your research.

Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments. 

References: 

1. Kanno, Y., Ota, R., Someya, K., Kusakabe, T., Kato, K., & Inouye, Y. (2013). Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biological and Pharmaceutical Bulletin, 36(9), 1460–1465. 
2. Yatsu, T., Kusakabe, T., Kato, K., Inouye, Y., Nemoto, K., & Kanno, Y. (2018). Selective               androgen Receptor modulator, YK11, Up-Regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biological and Pharmaceutical Bulletin, 41(3), 394–398. 
3. Kanno, Y., Saito, N., Saito, R., Kosuge, T., Shizu, R., Yatsu, T., Hosaka, T., Nemoto, K., Kato, K., & Yoshinari, K. (2022). Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453 cells. Experimental Cell Research, 419(2), 113333.