PT-141(Bremelanotide) Peptide Nasal Spray –  Product Details

PT-141, also known as Bremelanotide, is a synthetic peptide derived from Melanotan II and functions as a melanocortin receptor agonist. It primarily targets melanocortin receptors, especially MC3 and MC4, in experimental models, where it is studied for its role in central nervous system signaling pathways..

PT-141 has been investigated for its effects on neuroendocrine signaling and behavioral response pathways in research conditions. Its mechanism involves modulation of melanocortin receptors, which are associated with regulatory processes in the brain. These properties make it a subject of interest in studies exploring central signaling and receptor-mediated pathways.

PT-141 Nasal Spray is intended for laboratory research purposes only. It is not approved for human use or consumption.

Mechanism of Action of PT-141

PT-141 (bremelanotide) functions as a melanocortin receptor agonist, primarily interacting with MC3 and MC4 receptors in experimental models. Activation of these receptors has been shown to influence central nervous system signaling pathways, particularly those associated with neuroendocrine regulation and neurotransmitter activity. In research settings, this interaction is linked to modulation of dopaminergic pathways and downstream signaling processes. This highlights its relevance in studies of receptor-mediated neural mechanisms.

Properties of PT-141 (Bremelanotide) Peptide

• Molecular Formula: C50H68N14O10
• Synonyms: Bremelanotide, PT-141, UNII-6Y24O4F92S, 6Y24O4F92S, PT 141, PT141
• IUPAC Name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazole-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxylic acid
• Molecular Weight: 1025.2 g/mol
• CAS Number: 189691-06-3

Research Findings on PT-141 (Bremelanotide)

Research studies have shown the interaction of PT-141 with melanocortin receptors in the central nervous system. Studies in experimental animal models have shown that PT-141 activates neurons in regions such as the hypothalamus, as indicated by increased c-Fos expression, which is a marker of neuronal activity. These findings suggest that PT-141 plays a role in modulating central neural pathways linked to neuroendocrine signaling and receptor-mediated responses.

Studies focus on melanocortin receptor agonists like PT-141 and their effects on physiological and behavioral signaling pathways. Experimental studies indicate that activation of MC3 and MC4 receptors by PT-141 is associated with changes in neural signaling related to behavioral responses and central regulatory mechanisms. These observations highlight its relevance in research exploring melanocortin system pathways and their role in central nervous system activity, although further studies are required to fully understand these mechanisms.

Note: PT-141 is not approved by the FDA for medical use. It is available for investigational and research purposes only.

Why Choose BehemothLabz to Buy PT-141 (Bremelanotide) Peptide Nasal Spray?

BehemothLabz is committed to providing high-purity research compounds that meet rigorous quality control standards. We provide high-quality PT 141 Nasal Spray for sale. When you buy PT 141 Nasal Spray from BehemothLabz, you are selecting a product that has undergone extensive analytical testing for identity, purity, and stability—key attributes for any research setting.

Our team ensures that each batch is handled under GMP-compliant conditions to support scientific integrity and reproducibility. BehemothLabz has established a reputation among researchers for supplying consistent and reliable compounds tailored for investigative use.

Disclaimer

Please make sure you go through the Terms and Conditions, and please familiarize yourself with them as they are important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.

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ATTENTION: All Behemoth Labz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

Reference Links

PubChem. (2026). Bremelanotide. Nih.gov; PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Bremelanotide

MOLINOFF, P. B., SHADIACK, A. M., EARLE, D., DIAMOND, L. E., & QUON, C. Y. (2003). PT-141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction. Annals of the New York Academy of Sciences, 994(1), 96–102. https://doi.org/10.1111/j.1749-6632.2003.tb03167.x

Trevor J. Hallam, Carl Spana, Dennis C. Earle, Annette M. Shadiack, & Shubh D. Sharma. (2007). Melanocortins in the Treatment of Male and Female Sexual Dysfunction. Current Topics in Medicinal Chemistry, 7(11), 1137–1144. https://doi.org/10.2174/156802607780906681