Product Details: PNC-27 Peptide

PNC-27 is an artificially made peptide. It consists of a segment derived from the p53 protein fused to a cell-penetrating peptide sequence. It is designed for use in laboratory and preclinical research. It serves best in investigating peptide-membrane interactions and protein-targeting mechanisms in experimental models. PNC-27 has been studied for its ability to selectively bind to HDM-2. HDM-2 is the human double minute 2 protein. It is expressed in certain proliferative cell systems. This makes it a valuable compound for controlled studies in cellular and molecular biology.

Mechanism of Action

In preclinical and experimental models, PNC-27 has been seen to interact with HDM-2 proteins. These are expressed on the surface of specific cell types. Upon binding, the peptide may sync into the cellular membrane and facilitate the formation of transmembrane pore-like structures. This process is linked with disruption of membrane integrity and downstream cellular responses in controlled laboratory settings. These mechanisms help in understanding:

• peptide-induced membrane activity
• protein targeting, and 
• structural interactions at the cellular level

Properties of PNC-27 Peptide:

• Molecular Formula: C188H293N53O44S
• Molecular Weight: 4031.7 g/mol
• CAS Number: 129954-34-3
• PubChem CID: Not widely indexed
• Synonyms: PNC-27, p53-HDM2 targeting peptide
• IUPAC Name: Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly-OH

Research Applications/Benefits of PNC-27 Peptide

Protein-Target Interaction Studies

PNC-27 is used in laboratory research. It is done to see interactions between peptide ligands and HDM-2 protein in controlled experimental systems.

Membrane Interaction Research

The peptide is applied in preclinical models. This is basically done to study peptide-induced membrane disruption, pore formation, and structural changes in cellular membranes.

Peptide Design and Engineering

PNC-27 is a model compound for investigating the design of fusion peptides. Its studies combine targeting domains with cell-penetrating sequences.

Cellular Response Analysis

It is also used in experimental systems to evaluate cellular responses to membrane-active peptides. These also include structural and biochemical changes under controlled conditions.

Comparative Peptide Studies

PNC-27 is employed in research comparing different peptide constructs. It is done to assess specificity, binding characteristics, and functional activity in laboratory models.

Why Choose BehemothLabz to Buy PNC-27 Peptide

BehemothLabz is committed to delivering high-purity research peptides manufactured under strict quality control standards. Each batch of PNC-27 undergoes independent third-party testing to ensure verified purity, identity, and consistency. Researchers rely on BehemothLabz for dependable compounds that support reproducible and high-quality laboratory and preclinical investigations.

Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.

ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.