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Ostarine (MK-2866) Injectable Specifications
| Feature | Details |
|---|---|
| Product Name | Ostarine (MK-2866) Injectable |
| SKU | be-1778025205998-2 |
| Category | BEST RESEARCH SARMS |
| Price | $83.13 |
| Availability | In Stock / For Sale |
Detailed Description & Research
Product Details – MK-2866
MK-2866 is a synthetic small-molecule compound classified as a selective androgen receptor modulator (SARM). It is studied in biochemical research for its selective interaction with androgen receptors and its role in receptor-mediated signaling pathways.
In laboratory settings, MK-2866 is utilized to investigate ligand-receptor binding dynamics, nuclear receptor activation, and transcriptional modulation associated with androgen receptor signaling. Its nonsteroidal structure allows for targeted receptor interaction, making it a relevant compound in structure-function and signaling pathway studies.
Mechanism of Action
MK-2866 functions as a ligand for the androgen receptor (AR), a nuclear receptor involved in transcriptional regulation. Upon binding, the compound-receptor complex undergoes conformational changes that facilitate translocation into the cell nucleus.
Subsequently, the activated receptor complex interacts with androgen response elements (AREs) within DNA, leading to modulation of gene transcription. This process is studied in terms of coactivator recruitment, transcriptional regulation, and downstream signaling pathway activation.
Furthermore, MK-2866 is investigated for its selective receptor-binding properties, allowing researchers to analyze ligand specificity, receptor activation patterns, and intracellular signaling mechanisms in controlled experimental systems.
Chemical Properties of MK-2866
| Property | Value |
| Chemical Formula | C19H14F3N3O3 |
| Molar Mass | 393.4 g/mol |
| CAS Number | 841205-47-8 |
| Synonyms | MK-2866 |
| IUPAC Name | (2S)-3-(4-cyano-2,3,5,6-tetradeuteriophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide |
| PubChem CID | 45107712 |
Research Applications
Androgen Receptor Binding Studies
MK-2866 is widely used in laboratory research to examine ligand binding affinity and selectivity toward androgen receptors. These studies focus on receptor activation, conformational changes, and ligand-receptor complex stability.
Nuclear Receptor Signaling Analysis
In addition, the compound is applied in research investigating nuclear receptor-mediated signaling pathways. This includes analysis of receptor translocation, DNA binding, and transcriptional regulation via androgen response elements.
Structure–Activity Relationship (SAR) Studies
MK-2866 is utilized in SAR studies to evaluate how structural features influence receptor binding, signaling selectivity, and molecular interaction profiles.
Transcriptional Modulation Research
The compound is also relevant in studies examining gene expression pathways regulated by androgen receptor activation, including coactivator recruitment and downstream signaling cascades.
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Disclaimer
MK-2866 is intended strictly for laboratory research and analytical purposes only. It is not intended for use in diagnostic procedures, therapeutic applications, or in vivo studies of any kind.
Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes. This compound must be handled exclusively by qualified professionals in controlled laboratory environments in accordance with applicable regulations and safety guidelines.
Improper handling or use outside of controlled research settings is strictly prohibited.
References
- Komrakova, M., Nagel, J., Hoffmann, D. B., Lehmann, W., Schilling, A. F., & Sehmisch, S. (2020). Effect of Selective Androgen Receptor Modulator Enobosarm on Bone Healing in a Rat Model for Aged Male Osteoporosis. Calcified tissue international, 107(6), 593–602. https://doi.org/10.1007/s00223-020-00751-x
- Böker, K. O., Komrakova, M., Fahrendorff, L., Spelsberg, B. R., Hoffmann, D. B., Schilling, A. F., Lehmann, W., Taudien, S., & Sehmisch, S. (2023). Treatment of osteoporosis using a selective androgen receptor modulator ostarine in an orchiectomized rat model. Endocrine, 81(3), 579–591. https://doi.org/10.1007/s12020-023-03422-7
| Variation |
10ml / 64mg per ml / 640mg |
|---|
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External Resources
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